Your Workout May Help More Than You Think

Behind the Boost: When we think about what causes us to feel better after a run or a bike ride, we’re quick to credit endorphins with that mood boost (or, at least, this lawyer is). But new research indicates there could be another mechanism at play: our HDL (“good”) cholesterol levels. 

The Study: Researchers analyzed data from more than 16,500 adults in the National Health and Nutrition Examination Survey (NHANES). Those who hit the recommended 150 minutes of exercise a week had a 57% lower risk of depression compared to people who were less active. They also found higher levels of HDL cholesterol were independently associated with a lower risk of depression.

The Takeaway: The research demonstrates the connection among all three: exercise, HDL levels, and depression. HDL cholesterol protects more than just our arteries: It has neuroprotective and anti-inflammatory properties, too. Aerobic exercise and strength training can boost HDL levels, providing benefits for mental, cardiovascular, and metabolic health. Similarly, exercise helps with depression via multiple pathways, including decreased inflammation, stress and neurotransmitter regulation, and better sleep.

Keep in Mind: Much of the data was self-reported, and the study found only an association, not causation.