What Muscle Loss Could Mean for Your Brain Health

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Use It or Lose It: Muscle loss is common as we age. Sarcopenia is characterized by very low muscle mass, strength, or function. Over time, muscle decline can make everyday activities more difficult and increase the risk of dangerous falls and bone fractures. A recent review has found a link between sarcopenia and another debilitating age-related condition: dementia. 

The Study: A meta-analysis of 83 studies published between 2005 and 2026 was conducted to better understand the relationship between body composition, muscle health, and dementia. 14 of these studies looked specifically at sarcopenia, assessing the participant’s muscle health using measures like grip strength, walking speed, and muscle mass. 

The Takeaway: Researchers determined that people with sarcopenia had a 42% higher risk of dementia. Age made a difference among people with obesity: In those under 65, obesity was associated with a 9% higher risk of dementia, while in people 65 and older, it was associated with a 17% lower risk. There was no significant link between dementia risk and people with sarcopenic obesity (both excess body fat and low muscle mass).

Keep in Mind: The research found an association between sarcopenia and dementia risk, not causation, but it highlights the importance of maintaining strength and muscle mass as we age.


Stephanie Anderson Witmer is an award-winning health journalist and brand content writer based in Pennsylvania.…